Despite an increased understanding of the pathogenesis of nosocomial pneumo
nia and advances in diagnosis and treatment, the risk, cost, morbidity, and
mortality of nosocomial pneumonia remain unacceptably high. The authors id
entify specific risk factors for nosocomial pneumonia, including the host,
infection control practices, use of pharmacologic agents, and invasive devi
ces that are potential targets for prophylaxis. Data are presented from rec
ently published guidelines for prevention of nosocomial pneumonia that are
simple and cost effective but not commonly integrated into routine patient
care. The authors recommend that strategies for prophylaxis of nosocomial a
nd ventilator-associated pneumonia be implemented by a multidisciplinary te
am comprised of physicians (critical care, pulmonary medicine, infectious d
iseases, and primary care), critical care and infection control nurses, and
respiratory therapists. The goal should be better overall patient care, ev
en if it may result in decreased professional autonomy and freedom.