The economy of T-cell memory: CD4(+) recession in times of CD8(+) stability?

Authors
Whitmire, JK Ahmed, R
Citation
Jk. Whitmire et R. Ahmed, The economy of T-cell memory: CD4(+) recession in times of CD8(+) stability?, NAT MED, 7(8), 2001, pp. 892-893
Citations number
12
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research General Topics
Journal title
NATURE MEDICINE
ISSN journal
10788956 → ACNP
Volume
7
Issue
8
Year of publication
2001
Pages
892 - 893
Database
ISI
SICI code
1078-8956(200108)7:8<892:TEOTMC>2.0.ZU;2-3
Abstract
Although systemic viral infection gives rise to robust responses from both CD8(+) and CD4(+) T cells, there are striking differences as well as simila rities in the way the two classes of lymphocyte cells react. Insights into the patterns of response by each type of T cell could lead to the developme nt of new therapeutics that enhance or suppress factors governing CD8(+) an d CD4+ T-cell immunity.