Objective: To examine risk factors for nursing home placement in a communit
y-based dementia cohort. Methods: Cognitively normal participants and cogni
tively impaired patients from a large AD Patient Registry were followed fro
m diagnosis to placement, death, or last follow-up. This included over 3,60
0 person-years of surveillance. The normal group included 473 participants
who did not, at any point, meet Diagnostic and Statistical Manual of Mental
Disorders, 3rd ed., revised (DSM-III-R) criteria for dementia. The patient
group included 512 patients who met DSM-III-R criteria for dementia or cri
teria for mild cognitive impairment at diagnosis. Demographic, medical, soc
ial, cognitive, behavioral, and functional predictors of time to placement
were examined using Cox modeling. Results: In the normal group, only 21 peo
ple (4%) required nursing home placement. With subjects, enrollment year, a
ge at initial evaluation, being widowed, and living in a retirement communi
ty were associated with time to placement in separate univariate analyses.
Of 512 cognitively impaired patients, 203 (39.6%) were placed in nursing ho
mes. Median time from diagnosis to placement was 5.3 years. Within the pati
ent sample, four predictors were determined to be associated with time to n
ursing home placement. These included gender, enrollment year, functional s
tatus, and cognitive score. Interactions were present for functional status
with cognitive score and enrollment year. Conclusion: In patients with dem
entia who are within 5 years of diagnosis, placement rates of approximately
10% per year can be expected. Disease severity indices including degree of
cognitive and functional impairment are primary risk factors for placement
.