Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease

The authors studied the accuracy of clinical diagnosis of idiopathic PD (IP D) in 100 consecutive clinically diagnosed cases that came to neuropatholog ical examination. Ninety fulfilled pathologic criteria for IPD. Ten were mi sdiagnosed: multiple system atrophy (six), progressive supranuclear palsy ( two), post-encephalitic parkinsonism (one), and vascular parkinsonism (one) . Assessment of the clinical features suggests that an accuracy of 90% may be the highest that can be expected using current diagnostic criteria.