Pre-eclampsia: A predisposing factor for neonatal venous sinus thrombosis?

Neonatal venous sinus thrombosis is a well-recognized, but infrequently dia gnosed, cause of neonatal encephalopathy. Previous reports have tended to o mit reference to the importance of maternal factors in predisposing the inf ant to this condition. This report, in which eight patients with neonatal v enous sinus thrombosis are presented, will reveal a strong association betw een pre-eclampsia, prothrombotic disorders, and neonatal venous sinus throm bosis. Contrary to previously published reports, there is a high likelihood of neurodevelopmental residua after this condition. (C) 2001 by Elsevier S cience Inc. All rights reserved.