Borderline forms of multiple sclerosis

Multiple sclerosis (MS) has been described for more than a century, but its cause remains unknown and no simple diagnostic marker is available. Theref ore, it is not surprising that numerous articles were written on closely re lated diseases, borderline forms of multiple sclerosis. Different forms hav e been distinguished: a clinical form of MS (Devic's neuromyelitis optica), pathological forms (Balo, Schilder, Maburg), forms associated with MS (per ipheral neuropathy, autoantibodies) and closely related disorders (acute di sseminated encephalomyelitis).