The insensitivity of the clinical scales usually performed in MS patients l
ed to measure the quality of life (QoL). QoL includes several important dom
ains of health which are regarded by patients as being more important deter
minants of their overall health states. Some aspects of QoL of MS patients
(early collapse in the disease, impact of interferons therapy) suggested th
at its measurement is relevant in assessing the effect of treatment and pro
gression of the disease.