Comparative evaluation of clinical efficiency of intravenous laser radiation of blood, plasmapheresis alone and in combination in patients with bronchial asthma
Ti. Ishina et al., Comparative evaluation of clinical efficiency of intravenous laser radiation of blood, plasmapheresis alone and in combination in patients with bronchial asthma, TERAPEVT AR, 73(3), 2001, pp. 15-19
Aim. To compare clinical response to intravenous laser radiation of blood (
ILRB), plasmapheresis (PA) and ILRB+PA in patients with bronchial asthma (B
A).
Materials and methods. 122 patients with endogenic BA of moderate severity
were divided into four groups: group 1 was exposed to ILRB, group 2-to PA,
group 3-to ILRB+PA, group 4 received only chemotherapy. The effect was asse
ssed by body plethismography, peak flowmetry, NBT-test, LCP-test.
Results. Patients of group 1-3 vs group 4 demonstrated earlier disappearanc
e of cough and normalization of lung auscultative picture, lower demand of
oral glucocorticosteroids, 2 times longer remission, better external respir
ation function, earlier normalization of peak expiration flow. ILRB, PA and
ILRB+PA activate function of oxygen-dependent bactericidal system of blood
neutrophils and inhibited activity of non-oxygen-dependent system.
Conclusion. Combined treatment of moderate severity BA with ILRB, PA alone
and in combination is more effective than conventional drug therapy, the hi
ghest effect by remission terms being achieved in combination of ILRB with
PA.