A short formal synthesis of paroxetine. Diastereoselective cuprate addition to a chiral racemic olefinic amido ester

Authors
Cossy, J Mirguet, O Pardo, DG Desmurs, JR
Citation
J. Cossy et al., A short formal synthesis of paroxetine. Diastereoselective cuprate addition to a chiral racemic olefinic amido ester, TETRAHEDR L, 42(44), 2001, pp. 7805-7807
Citations number
24
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
44
Year of publication
2001
Pages
7805 - 7807
Database
ISI
SICI code
0040-4039(20011029)42:44<7805:ASFSOP>2.0.ZU;2-8
Abstract
A diastereoselective conjugate addition of an organocopper reagent to a chi ral racemic olefinic amido ester has been used as the key step in a formal total synthesis of paroxetine. (C), 2001 Published by Elsevier Science Ltd.