An enantio- and stereocontrolled route to epopromycin B via cinchona alkaloid-catalyzed Baylis-Hillman reaction

Authors
Iwabuchi, Y Sugihara, T Esumi, T Hatakeyama, S
Citation
Y. Iwabuchi et al., An enantio- and stereocontrolled route to epopromycin B via cinchona alkaloid-catalyzed Baylis-Hillman reaction, TETRAHEDR L, 42(44), 2001, pp. 7867-7871
Citations number
22
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
44
Year of publication
2001
Pages
7867 - 7871
Database
ISI
SICI code
0040-4039(20011029)42:44<7867:AEASRT>2.0.ZU;2-K
Abstract
An enantio- and stereocontrolled route to epopromycin B having the epoxy-be ta -aminoketone pharmacophore is developed based on the cinchona alkaloid-c atalyzed Baylis-Hillman reaction of N-Fmoc-leucinal. (C) 2001 Elsevier Scie nce Ltd. All rights reserved.