Synthetic studies toward the total synthesis of kaitocephalin 1. whose ster
eochemical assignment was undetermined at the time of commencement. were un
dertaken in an attempt to provide a general methodology to gain access to a
ny one of all 32 possible stereoisomers. An interesting, unexpected, result
was observed in the anticipated stereoselective key aldol reaction. (C) 20
01 Published by Elsevier Science Ltd.