Intracavitary therapy of noninvasive transitional cell carcinomas of the upper urinary tract - A review of the literature

Noninvasive (stages Ta, T1, Tis) transitional cell carcinomas of the upper urinary tract are suitable for a conservative therapeutic approach. Intraca vitary therapy (alone or as adjuvant treatment) has recently been proposed and successfully used by some authors. Even though bacillus Calmette-Guerin is the most frequent agent employed, chemotherapeutic drugs, such as mitom ycin C and thiotepa, have also been successfully used. The current informat ion available in the literature is therefore reviewed. According to the dat a available, intracavitary therapy is a worthwhile conservative therapeutic option for noninvasive upper urinary tract urotheliomas with acceptable si de effects. For this reason it may be included in the routine urological ar mamentarium.