We examined 330 patients with ischemic stroke and chronic cerebrovascular d
isease (CVD). 48 healthy volonteers were also observed. in both patients an
d controls we studied risk factors and data acquired by Doppler investigati
on of extra- and intracranial vessels, brain MRI and CT. We describe the fo
llow-up of risk factors in patients with chronic CVD including those cases
in which stroke ensued as complication.