National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) - Alzheimer disease trial methodology

Authors
Schneider, LS Tariot, PN Lyketsos, CG Dagerman, KS Davis, KL Davis, S Hsiao, JK Jeste, DV Katz, IR Olin, JT Pollock, BG Rabins, PV Rosenheck, RA Small, GW Lebowitz, B Lieberman, JA
Citation
Ls. Schneider et al., National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) - Alzheimer disease trial methodology, AM J GER PS, 9(4), 2001, pp. 346-360
Citations number
43
Categorie Soggetti
Psychiatry,"Clinical Psycology & Psychiatry
Journal title
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
ISSN journal
10647481 → ACNP
Volume
9
Issue
4
Year of publication
2001
Pages
346 - 360
Database
ISI
SICI code
1064-7481(200123)9:4<346:NIOMHC>2.0.ZU;2-1
Abstract
The authors describe the development of the Clinical Antipsychotic Trials o f Intervention Effectiveness (CATIE) protocol for Alzheimer disease (AD), a trial developed in collaboration with the National Institute of Mental Hea lth (NIMH), assessing the effectiveness of atypical antipsychotics for psyc hosis and agitation occurring in AD outpatients. They provide an overview o f the methodology utilized in the trial as well as the clinical-outcomes an d effectiveness measures that were implemented.