An automated technique for measuring hippocampal volumes from MR imaging studies

Authors
Gosche, KM Mortimer, JA Smith, CD Markesbery, WR Snowdon, DA
Citation
Km. Gosche et al., An automated technique for measuring hippocampal volumes from MR imaging studies, AM J NEUROR, 22(9), 2001, pp. 1686-1689
Citations number
12
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Neurosciences & Behavoir
Journal title
AMERICAN JOURNAL OF NEURORADIOLOGY
ISSN journal
01956108 → ACNP
Volume
22
Issue
9
Year of publication
2001
Pages
1686 - 1689
Database
ISI
SICI code
0195-6108(200110)22:9<1686:AATFMH>2.0.ZU;2-M
Abstract
We describe an automated volumetric measure of the hippocampus obtained wit h software called the Knowledge-Guided MRI Analysis Program (KGMAP). Postmo rtem MR images from 56 participants in the Nun Study were used to validate the measure. KGMAP-determined volumes strongly correlated with those obtain ed with manual tracings and neurofibrillary pathologic findings of Alzheime r disease in the hippocampus. KGMAP provides a rapid and accurate estimate of hippocampal volume that is suitable for use in clinical practice.