Characterisation of Shah convolution Fourier transform detection

Multiple-point (Shah function) detected, time-domain detector signals were converted into frequency-domain plots by means of Fourier transformation. S ignal-to-noise ratio enhancement by Shah convolution Fourier transform dete ction (SCOFF), compared with single-point detection, was obtained. Hence SC OFF could lower the detection limits and have many potential applications i n trace analysis. The frequency of the fundamental peak obtained by SCOFF i ncreases linearly with increasing migration velocity of the analyte. SCOFT is capable of extracting multiple frequency components contained in the tim e-domain detector signals, e.g., in a separation. Hence SCOFT could be used to interrogate a separation based on the differences in the migration velo cities of the compounds in the mixture.