Ion-channel sensing of ferricyanide anion based on a supported bilayer lipid membrane

Ferricyanide anion has usually been used as a marker of ion-channel sensors . In this work we first found that ferricyanide, itself, can act as a stimu lus to regulate the permeability of sBLM prepared from didodecyldimethylamm onium bromide (a kind of synthetic lipid) on a GC electrode. We used cyclic voltammetry and a.c. impedance to investigate this phenomenon. The interac tion between sBLM and ferricyanide concerns time. Furthermore, we developed a sensor for ferricyanide anion. The ion-channel sensor is highly sensitiv e. It can detect ferricyanide concentration as low as 5 muM.