Synthetic cells-self-assembling polymer membranes and bioadhesive colloids

We summarize developments in the construction of synthetic cells made from polymers, with a particular focus on mimicking the structure and behavior o f blood cells. Two basic themes emerge-the use of block copolymers to make polmer vesicles and the functionalization of colloidal or polymeric microsp heres with cell-like adhesive properties. Both platforms provide a means fo r building the complex hierarchy that is characteristic of biological cells , while also incorporating novel and perhaps superior properties of materia l strength, specific targeting, and controlled release.