Ml. Check et al., Pregnancy/implantation rates as related to age following transfer of frozen embryos produced by ICSI, ARCH ANDROL, 47(3), 2001, pp. 161-165
A study has suggested that one drawback of ICSI is that if these embryos ar
e cryopreserved they have lower implantation rates after thawing and transf
er as compared to other frozen embryos derived from conventional oocyte ins
emination. Other studies have not shown such adverse effects on pregnancy r
ates following frozen embryo transfer (ET) of embryos formed by ICSI. The s
tudy presented here evaluated the largest number of frozen ET cycles of emb
ryos following ICSI, which were compared to couples having frozen ET with e
mbryos formed by conventional insemination. In women age 39 and younger, th
e clinical, viable, pregnancy rates and implantation rates were very simila
r. Similar rates were reached for tile older group. These data convincingly
demonstrate that fertilization by ICSI does not adversely effect the impla
nting capacity of frozen-thawed embryos.