Effect of testosterone replacement therapy on serum PSA in patients with Klinefelter syndrome

Authors
Shibasaki, T Sasagawa, I Suzuki, Y Yazawa, H Ichiyanagi, O Matsuki, S Miura, M Nakada, T
Citation
T. Shibasaki et al., Effect of testosterone replacement therapy on serum PSA in patients with Klinefelter syndrome, ARCH ANDROL, 47(3), 2001, pp. 173-176
Citations number
16
Categorie Soggetti
da verificare
Journal title
ARCHIVES OF ANDROLOGY
ISSN journal
01485016 → ACNP
Volume
47
Issue
3
Year of publication
2001
Pages
173 - 176
Database
ISI
SICI code
0148-5016(200111/12)47:3<173:EOTRTO>2.0.ZU;2-V
Abstract
The effect of testosterone replacement therapy on serum prostate-specific a ntigen (PSA) was investigated in 11 patients with Klinefelter syndrome. Sig nificant increases in serum testosterone level and prostate volume were obs erved after testosterone replacement therapy. However, serum PSA level did not change after testosterone replacement therapy. It would appear that ser um PSA is not influenced by exogenous testosterone in patients with Klinefe lter syndrome.