One-pot synthesis of cinnamylamines with various protecting groups from cinnamyl ethers

Authors
Citation
Yh. Jung et Jd. Kim, One-pot synthesis of cinnamylamines with various protecting groups from cinnamyl ethers, ARCH PH RES, 24(5), 2001, pp. 371-376
Citations number
35
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ARCHIVES OF PHARMACAL RESEARCH
ISSN journal
02536269 → ACNP
Volume
24
Issue
5
Year of publication
2001
Pages
371 - 376
Database
ISI
SICI code
0253-6269(200110)24:5<371:OSOCWV>2.0.ZU;2-T
Abstract
The reaction of various alkyl cinnamyl ethers with CSI afforded the corresp onding cinnamylamines with various protecting groups, such as -NHMoc, -NHiP oc, -NHCbz, NHPnz, -NHTroc and -NHAloc. In the case of cinnamyl t-butyl eth er and cinnamyl p-methoxybenzyl ether, the corresponding cinnamyl carbamate s were formed via a different reaction pathway from the above.