Synthesis and cytotoxicity against human cancer cells of novel diazenecarboxamides

Citation
L. Pieters et al., Synthesis and cytotoxicity against human cancer cells of novel diazenecarboxamides, ARKIVOC, 2, 2001, pp. NIL_63-NIL_70
Citations number
16
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
Volume
2
Year of publication
2001
Part
3
Pages
NIL_63 - NIL_70
Database
ISI
SICI code
Abstract
The synthesis as well as the cytotoxic activity of a series of diazenecarbo xamides 1a-1j, which are stable representatives of the diazene family, in a human cancer cell line panel are described. Compounds 1j and especially 1g showed a high cytotoxic activity against some leukemia cell lines, and can be considered as new leads for further development.