A case of early-onset benign occipital seizure susceptibility syndrome: decreased cerebral blood flow in the occipital region detected by interictal single photon emission computed tomography, corresponding to the epileptogenic focus
M. Sakagami et al., A case of early-onset benign occipital seizure susceptibility syndrome: decreased cerebral blood flow in the occipital region detected by interictal single photon emission computed tomography, corresponding to the epileptogenic focus, BRAIN DEVEL, 23(6), 2001, pp. 427-430
Early-onset benign childhood occipital seizure susceptibility syndrome (EBO
SS) recently described by Panayiotopoulos, is an early-onset variant of ben
ign childhood epilepsy with occipital paroxysms. EBOSS is characterized by
partial seizures that are predominantly manifested at night and associated
with deviation of the eyes, vomiting and impairment of consciousness, but w
ithout ictal visual symptoms or postictal headache. The clinical features o
f our case were consistent with those of EBOSS, and we therefore diagnosed
the patient as having a typical form of EBOSS. Neuroimaging by CT, MRI and
MR angiography did not reveal a focal lesion. Interictal single photon emis
sion computed tomography (SPECT) revealed decreased cerebral blood flow in
the right occipital region corresponding to the epileptogenic focus shown o
n EEG. It remains unclear whether our finding on SPECT reflects secondary h
ypoperfusion due to minor morphological abnormality or immediate functional
hypoperfusion. No reference to SPECT in a case of EBOSS has appeared in th
e literature to date. This report provides a better understanding of benign
childhood epileptic syndromes with occipital spikes. (C) 2001 Elsevier Sci
ence B.V. All rights reserved.