Computer simulations of lung airway structures using data-driven surface modeling techniques

Citation
Rm. Spencer et al., Computer simulations of lung airway structures using data-driven surface modeling techniques, COMPUT BIOL, 31(6), 2001, pp. 499-511
Citations number
40
Categorie Soggetti
Multidisciplinary
Journal title
COMPUTERS IN BIOLOGY AND MEDICINE
ISSN journal
00104825 → ACNP
Volume
31
Issue
6
Year of publication
2001
Pages
499 - 511
Database
ISI
SICI code
0010-4825(200111)31:6<499:CSOLAS>2.0.ZU;2-O
Abstract
Knowledge of human lung morphology is a subject critical to many areas of m edicine. The visualization of lung structures naturally lends itself to com puter graphics modeling due to the large number of airways involved and the complexities of the branching systems. In this study, a method of generati ng three-dimensional computer simulations of human lung airway networks usi ng data-driven, surface modeling techniques is presented. By simulating the tubular airway structures and realistic bifurcation shapes, anatomically a ccurate representations of human lungs are obtained. These computer models are designed for use in computational fluid dynamic applications and partic le trajectory analyses, and to be complimentary to medical imaging (gamma s cintigraphy) protocols. (C) 2001 Published by Elsevier Science Ltd.