The incidence of atopic allergy is increasing in certain 'Western' countrie
s but this remains unexplained. Various hypotheses with differing amounts o
f evidence and/or relevance have been assessed, including increased awarene
ss of the diseases, improved diagnostics, genetic susceptibility, psycho-so
cial influences, allergen exposure, decreased immune-system stimulation, un
derlying disease, anti-allergic therapy and pollution.