The finite difference approximation is applied to estimate the moisture-dep
endent diffusion coefficient by utilizing test data of isothermal moisture
desorption in northern red oak (Quercus rubra). The test data contain moist
ure distributions at discrete locations across the thickness of specimens,
which coincides with the radial direction of northern red oak, and at speci
fied times. Also, the rate of moisture variation at each specified time and
location must be known or correctly estimated. The functional form of the
diffusion coefficient as well as the boundary conditions at the surfaces ar
e not known a priori. The resulting system of finite difference equations d
efines an inverse problem, whose solution may be sensitive to small changes
of input data. Results indicate that the diffusion coefficient increases w
ith increasing moisture content below the fiber saturation point, which def
ines the upper limit applied by the diffusion theory.