PLE catalysed enantiomeric separation of various (+/-)-6-acetoxy-alpha,beta-unsaturated cyclic ketones

Authors
Tanyeli, C Sezen, B Dikici, E Fleischhauer, J Repges, C Wang, YK Gawronski, J Kacprzak, K
Citation
C. Tanyeli et al., PLE catalysed enantiomeric separation of various (+/-)-6-acetoxy-alpha,beta-unsaturated cyclic ketones, ENANTIOMER, 6(4), 2001, pp. 219-227
Citations number
27
Categorie Soggetti
Chemistry
Journal title
ENANTIOMER
ISSN journal
10242430 → ACNP
Volume
6
Issue
4
Year of publication
2001
Pages
219 - 227
Database
ISI
SICI code
1024-2430(2001)6:4<219:PCESOV>2.0.ZU;2-Q
Abstract
Various (+/-)-6-acetoxy-alpha,beta -unsaturated cyclic ketones were resolve d by PLE catalysed hydrolysis to afford enantiomerically enriched 6-hydroxy derivatives with 85-98% e.e. The absolute configuration of 6-hydroxy-alpha ,beta -unsaturated cyclic ketones were determined via CD measurements.