BRAIN METASTASIS IN MALIGNANT PLEURAL MESOTHELIOMA

A 55-year-old male who had a remote history of occupational asbestos e xposure consulted us because of chest pain. Chest X-ray revealed diffu se pleural thickening and pleural effusion on the right. A diagnosis o f malignant mesothelioma, biphasic type was made by needle pleural bio psy. Fourteen months later, the patient died of brain metastasis. At a utopsy, malignant mesothelioma of the pleura with metastasis to the br ain and bilateral adrenal glands was observed. Brain metastases proven by autopsy are rare in cases of malignant mesothelioma. The ferrugino us body count in the lung tissue was 16 per gram of wet weight.