ACUTE MYELOID-LEUKEMIA ACCOMPANIED BY MULTIPLE THROMBOPHLEBITIS

Authors
TSUMITA Y MATSUSHIMA T UCHIUMI H NARAHARA N TAMURA J KARASAWA M MURAKAMI H NARUSE T
Citation
Y. Tsumita et al., ACUTE MYELOID-LEUKEMIA ACCOMPANIED BY MULTIPLE THROMBOPHLEBITIS, Internal medicine, 36(8), 1997, pp. 595-597
Citations number
5
Categorie Soggetti
Medicine, General & Internal
Journal title
Internal medicine → ACNP
ISSN journal
09182918
Volume
36
Issue
8
Year of publication
1997
Pages
595 - 597
Database
ISI
SICI code
0918-2918(1997)36:8<595:AMABMT>2.0.ZU;2-B
Abstract
A 66-year-old woman suffering from fever and thrombophlebitis was refe rred to our hospital. A peripheral blood examination revealed hyperleu kocytosis with 96% blast cells and thrombocytopenia. The patient was d iagnosed as having acute myeloid leukemia (AML) accompanied by dissemi nated intravascular coagulation (DIC). A marked decrease in protein C (PC) antigen and activity were observed. In this case, PC levels were lower than those observed in AML with DIC. Induction therapy for leuke mia and treatment of DIC were started on the first day of hospitalizat ion. The patient achieved complete remission, with PC antigen and acti vity levels normalized.