M. Odeh et al., Bowel perforation due to gastrointestinal autonomic nerve tumour associated with neurofibromatosis type 1, EUR J GASTR, 13(10), 2001, pp. 1265-1268
Gastrointestinal autonomic nerve (GAN) tumours form a distinct subcategory
of gastrointestinal stromal tumours, and are thought to originate from the
enteric autonomic plexus. To date, a total of 45 cases have been documented
in the literature; a few of these cases were associated with neurofibromat
osis type 1 (NF-1). Bowel perforation due to other gastrointestinal stromal
tumours has been reported only twice, but never in association with a GAN
tumour. We describe a 40-year-old woman with NF-1 who had bowel perforation
due to a GAN tumour. The patient underwent radical surgical resection and
remained tumour free for at least 4 years, which may indicate a good progno
sis. Eur J Gastroenterol Hepatol 13:1265-1268 (C) 2001 Lippincott Williams
& Wilkins.