Arteriosclerosis in the influx and intravisceral arteries of the liver, kidney and lung of WHHL rabbits

dWe performed a histopathological investigation on arteriosclerotic develop ment in the influx and intra visceral arteries of the liver, kidney and lun g of male WHHL rabbits. In the influx arteries of these organs, we observed severe atherosclerotic vascular lesions with high-grade luminal stenosis. In the intravisceral arteries of the liver and kidney, no arteriosclerotic lesions were observed. However, in the intrapulmonary arteries, we recogniz ed severe atherosclerotic vascular changes with high-grade stenosis or tota l obstruction of the lumen in some middle to large sized pulmonary arteries . These observations indicate that the development of arteriosclerosis in p arenchymatous organs differs, and that some organs are predisposed to arter iosclerosis formation.