Complete response of a stage IV mucinous cystadenocarcinoma of the ovary to systemic chemotherapy employing paclitaxel and carboplatin

Background. The survival rate of patients with advanced-stage mucinous cyst adenocarcinoma of the ovary is dismal and no best treatment is known. We re port a case of complete response of a stage IV mucinous cystadenocarcinoma of the ovary to systemic chemotherapy employing paclitaxel and carboplatin. Case: A 51-year-old nullipara diagnosed with International Federation of G ynecology and Obstetrics stage IV mucinous cystadenocarcinoma of the ovary underwent cytoreductive surgery followed by systemic chemotherapy employing paclitaxel and carboplatin every 4 weeks for 3 courses. The patient tolera ted chemotherapy well, demonstrated a remarkable response showing no eviden ce of malignancy at a second-look laparotomy. As a consolidation chemothera py after negative second-look laparotomy, she underwent another three cours es of chemotherapy of the same regimen, and is showing no evidence of disea se. Conclusion: Paclitaxel and carboplatin may be effective in treating muc inous cystadenocarcinoma of the ovary. Copyright (C) 2001 S. Karger AG, Bas el.