The first substituted boranonucleic acids: a novel synthetic route

Authors
Vyakaranam, K Rana, G Spielvogel, BF Hosmane, NS
Citation
K. Vyakaranam et al., The first substituted boranonucleic acids: a novel synthetic route, INORG CH C, 4(11), 2001, pp. 629-631
Citations number
16
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
INORGANIC CHEMISTRY COMMUNICATIONS
ISSN journal
13877003 → ACNP
Volume
4
Issue
11
Year of publication
2001
Pages
629 - 631
Database
ISI
SICI code
1387-7003(200111)4:11<629:TFSBAA>2.0.ZU;2-1
Abstract
Diethylchlorophosphite-cyanoborane (1) was prepared in 65% yield by the rea ction of sodium cyanoborohydride and bromine followed by refluxing with die thylchlorophosphite. Compound 1 was reacted further with several commercial ly available nucleosides to give substituted boranonucleic acids in 46-91% yields. (C) 2001 Elsevier Science B.V. All rights reserved.