A. Olaitan et al., A critical evaluation of current protocols for the follow-up of women treated for gynecological malignancies: A pilot study, INT J GYN C, 11(5), 2001, pp. 349-353
This retrospective review was undertaken to determine the efficacy of routi
ne follow-up in the detection and management of recurrent cancer. The case
notes of all women attending a regional cancer center who were diagnosed wi
th cancer in 1997 were reviewed. Of 81 new cancers followed up for a median
of 42 months (range 36-48),14 have recurred after curative treatment and t
here were six cases of persistent disease. The median number of clinic visi
ts per patient was 3.5 (range 1-16). Eight recurrences (57.1%) were diagnos
ed at scheduled outpatient appointments, three (21.4%) presented to the gen
eral practitioner (GP), and three were seen as emergencies in hospital. Sev
enteen patients with persistent/recurrent disease have died and three are a
live with disease. The median time from initial presentation to disease rec
urrence was 12 months (range 5-25) and the median time from recurrence to d
eath was 5 months (range 1-20). The longest interval between onset of sympt
oms and diagnosis of recurrence (4 months) occurred in those presenting at
scheduled outpatient clinics. This study demonstrates that the current foll
ow-up protocol is associated with delays in diagnosing recurrence, because
symptomatic patients postpone seeking help until their scheduled visit. We
have therefore commenced a prospective study evaluating other models of fol
low-up.