Endocrine sequelae of cancer therapy in childhood

New treatments for neoplastic diseases of childhood have significantly incr eased patients' long-term survival and the importance of recognizing and co rrecting late complications of medical therapy. In this review, we examine both central nervous system (CNS) and non-CNS-related endocrine morbidities associated with chemotherapy and radiation therapy of childhood cancer. Th ese include effects on growth, puberty, fertility, thyroid and adrenal func tion which may present many years after the successful treatment of underly ing disease. (C) 2001, Editrice Kurtis.