The pathogenicity of Leucocytozoon caulleryi against specific-patho.-en-fre
e laying hens was investigated. Many large schizonts (second-generation sch
izonts) of L. caulleryi were seen in the ovary and oviducts of chickens. Ed
ema and pressure atrophy of the adjacent tissues were associated with these
schizonts. The eggshell-secreting portion of the uterus exhibited the most
severe damage in the oviduct. This experiment reconfirms that L. caulleryi
may stop egg production in laying hens, presumably as a result of damage t
o ovaries and oviducts.