2,2,6,6-tetramethyl-1-piperidinyl-oxyl/[bis(acetoxy)-iodo]benzene-mediatedoxidation: A versatile and convenient route to poly(ethylene glycol) aldehyde or carboxylic acid derivatives

Authors
Masson, C Scherman, D Bessodes, M
Citation
C. Masson et al., 2,2,6,6-tetramethyl-1-piperidinyl-oxyl/[bis(acetoxy)-iodo]benzene-mediatedoxidation: A versatile and convenient route to poly(ethylene glycol) aldehyde or carboxylic acid derivatives, J POL SC PC, 39(22), 2001, pp. 4022-4024
Citations number
22
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
ISSN journal
0887624X → ACNP
Volume
39
Issue
22
Year of publication
2001
Pages
4022 - 4024
Database
ISI
SICI code
0887-624X(20011115)39:22<4022:2>2.0.ZU;2-J
Abstract
A new and very convenient route to oxidized poly(ethylene glycol), with a c atalytic nitroxyl radical oxidant (2,2,6,6-tetramethyl-1-piperidinyl-oxyl) regenerated in situ by stoichiometric amounts of [bis(acetoxy)-iodo]benzene , is described. Under these conditions, the reaction is quantitative and le ads to the pure product by a simple process such as precipitation and washi ng with diethyl ether. (C) 2001 John Wiley & Sons, Inc.