Objective: To compare group therapy with routine care in adolescents who ha
d deliberately harmed themselves on at least two occasions within a year. M
ethod: Single-blind pilot study with two randomized parallel groups that to
ok place in Manchester, England. Sixty-three adolescents aged 12 through 16
years were randomly assigned to group therapy and routine care or routine
care alone. Outcome data on suicide attempts were obtained without knowledg
e of treatment allocation on all randomized cases (62/63 by direct intervie
w) on average 29 weeks later, The primary outcomes were depression and suic
idal behavior. Results: In intention-to-treat analyses, adolescents who had
group therapy were less likely to be "repeaters" at the end of the study (
i.e., to have repeated deliberate self-harm on two or more further occasion
s) than adolescents who had routine care (2/32 versus 10/31; odds ratio 6.3
), but the confidence intervals for this ratio were wide (95% confidence in
terval 1.4 to 28.7). They were also less likely to use routine care, had be
tter school attendance, and had a lower rate of behavioral disorder than ad
olescents given routine care alone. The interventions did not differ, howev
er, in their effects on depression or global outcome. Conclusions: Group th
erapy shows promise as a treatment for adolescents who repeatedly harm them
selves, but larger studies are required to assess more accurately the effic
acy of this intervention.