Isotretinoin (13-cis-retinoic acid) is a retinoid that has been used over t
he past 2 decades to treat a wide variety of dermatologic conditions, some
with great success. Although it is beneficial in many skill conditions, the
side effects and toxicities of oral retinoids require careful monitoring b
y experienced physicians. The clinical applications of Oral retinoids conti
nue to expand both within and beyond the field of dermatology.