A practical protocol for the synthesis of 3-hydroxy-4,5-disubstituted pyridine derivatives from acyclic compounds

Citation
L. Anastasia et al., A practical protocol for the synthesis of 3-hydroxy-4,5-disubstituted pyridine derivatives from acyclic compounds, J CHEM S P1, (19), 2001, pp. 2404-2408
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
14727781 → ACNP
Issue
19
Year of publication
2001
Pages
2404 - 2408
Database
ISI
SICI code
1472-7781(20011007):19<2404:APPFTS>2.0.ZU;2-H
Abstract
The paper reports a simple protocol for assembling a 3-hydroxy-4,5-disubsti tuted pyridine ring by reaction of allylamine or benzylamine and an alpha - bromo ketone and successive N-dealkylation.