Stereotactic radiotherapy using linear accelerator in patients with brain metastases

Citation
Al. Grosu et al., Stereotactic radiotherapy using linear accelerator in patients with brain metastases, NERVENARZT, 72(10), 2001, pp. 770-781
Citations number
53
Categorie Soggetti
Neurology
Journal title
NERVENARZT
ISSN journal
00282804 → ACNP
Volume
72
Issue
10
Year of publication
2001
Pages
770 - 781
Database
ISI
SICI code
0028-2804(200110)72:10<770:SRULAI>2.0.ZU;2-Q
Abstract
The aim of the study was to analyze the results of stereotactic radiotherap y using a linear accelerator in patients with brain metastases. We quantifi ed the following clinical parameters: tumor response and tumor control afte r therapy, survival, and side effects. Results of the treatment were compar ed with those from traditional treatment strategies such as surgery and who le brain irradiation. Sixty patients with brain metastases (80 lesions, 36 men and 24 women, mean age 57 years) were treated with stereotactic radioth erapy. The mean follow-up time was 13 months. Conclusion: Stereotactic radiotherapy is an important option in the treatme nt strategy for patients with brain metastases. In comparison to whole brai n irradiation, stereotactic radiotherapy achieved a higher local tumor cont rol with a lower rate of side effects. In comparison to surgery, stereotact ic radiotherapy has the advantages of shorter treatment time and lower trea tment-related morbidity and mortality.