Syntheses of analogues of the insect neuropeptide proctolin containing an oxazole ring as an amide bond replacement

Authors
Plant, A Stieber, F Scherkenbeck, J Losel, P Dyker, H
Citation
A. Plant et al., Syntheses of analogues of the insect neuropeptide proctolin containing an oxazole ring as an amide bond replacement, ORG LETT, 3(22), 2001, pp. 3427-3430
Citations number
27
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
22
Year of publication
2001
Pages
3427 - 3430
Database
ISI
SICI code
1523-7060(20011101)3:22<3427:SOAOTI>2.0.ZU;2-H
Abstract
[GRAPHICS] Three oxazole analogues of the insect neuropeptide proctolin (H-Arg-Tyr-Leu -Pro-Thr-OH) have been prepared, containing a single oxazole between Tyr an d Pro and between Pro and Thr, respectively. A compound containing an oxazo le moiety between Tyr and Pro and between Pro and Thr has also been prepare d. All compounds have been tested for myotropic activity.