A short and efficient route to novel scyphostatin analogues

Authors
Runcie, KA Taylor, RJK
Citation
Ka. Runcie et Rjk. Taylor, A short and efficient route to novel scyphostatin analogues, ORG LETT, 3(21), 2001, pp. 3237-3239
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
21
Year of publication
2001
Pages
3237 - 3239
Database
ISI
SICI code
1523-7060(20011018)3:21<3237:ASAERT>2.0.ZU;2-F
Abstract
[GRAPHICS] Several novel scyphostatin analogues have been prepared in up to 18% yield over five steps from commercially available 4-bromogualacol, utilizing an o rganometallic addition to afford the desired syn-hydroxy-epoxides.