We report on a scanning superconducting quantum interference device microsc
ope operating at temperatures down to 20 mK in a dilution refrigerator. The
instrument is designed for studying quantum mechanical coherence effects i
n mesoscopic systems and investigating magnetic effects on a mesoscopic len
gth scale in novel materials. We have demonstrated the low-temperature oper
ating capabilities of the instrument by studying superconducting tin disks
and the superconducting transition of a thin-film tungsten sample and vorti
ces in the same film. Looking forward, we discuss the applicability of the
instrument to measurements of persistent currents in normal-metal rings. (C
) 2001 American Institute of Physics.