Neuro-ophthalmology of mitochondrial diseases

Authors
Biousse, V Newman, NJ
Citation
V. Biousse et Nj. Newman, Neuro-ophthalmology of mitochondrial diseases, SEM NEUROL, 21(3), 2001, pp. 275-291
Citations number
145
Categorie Soggetti
Neurology
Journal title
SEMINARS IN NEUROLOGY
ISSN journal
02718235 → ACNP
Volume
21
Issue
3
Year of publication
2001
Pages
275 - 291
Database
ISI
SICI code
0271-8235(2001)21:3<275:NOMD>2.0.ZU;2-W
Abstract
The afferent and efferent visual pathways within the central nervous system are frequently involved in mitochondrial diseases. Neuro-ophthalmic signs figure prominently and may be the presenting or even sole manifestation of these disorders. The four most common neuro-ophthalmic abnormalities seen i n mitochondrial disorders are bilateral optic neuropathy, ophthalmoplegia w ith ptosis, pigmentary retinopathy, and retrochiasmal visual loss.