The synthetic potential of three-membered ring aza-heterocycles

Citation
B. Zwanenburg et P. Ten Holte, The synthetic potential of three-membered ring aza-heterocycles, T CURR CHEM, 216, 2001, pp. 93-124
Citations number
82
Categorie Soggetti
Current Book Contents
ISSN journal
03426793
Volume
216
Year of publication
2001
Pages
93 - 124
Database
ISI
SICI code
0342-6793(2001)216:<93:TSPOTR>2.0.ZU;2-5
Abstract
Functionalized aziridines, especially aziridine-2-carboxylic esters, are hi ghly valuable small-ring heterocycles for the synthesis of a large variety of anomalous amino acids, new types of ligands for catalytic purposes, new synthons, and four- and five-membered ring heterocycles through ring expans ion reactions. This review highlights the aziridine chemistry with the focu s on the utility of aziridine esters. The synthesis and chemistry of the hi ghly strained azirine carboxylic esters is also briefly reviewed.