Solvent-free synthesis of 4,4-bis-functionalized-1,6-dienes and 1,6-diyneson the surface of neutral alumina

Authors
Bhar, S Chaudhuri, SK Sahu, SG Panja, C
Citation
S. Bhar et al., Solvent-free synthesis of 4,4-bis-functionalized-1,6-dienes and 1,6-diyneson the surface of neutral alumina, TETRAHEDRON, 57(43), 2001, pp. 9011-9016
Citations number
22
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
43
Year of publication
2001
Pages
9011 - 9016
Database
ISI
SICI code
0040-4020(20011022)57:43<9011:SSO4A1>2.0.ZU;2-M
Abstract
An improved procedure has been developed for the synthesis of structurally varied 4,4-bis-functionalized-1,6-dienes and 1,6-diynes through regioselect ive alkylation of active methylene compounds with several unsymmetrical all yl bromides and propargyl bromide on the surface of neutral alumina impregn ated with sodium ethoxide or potassium tert-butoxide in the absence of any solvent under environmentally benign conditions. (C) 2001 Elsevier Science Ltd. All rights reserved.