A new concise synthesis of nectrisine and its facile conversion to phosphonoazasugars

Authors
Bosco, M Bisseret, P Bouix-Peter, C Eustache, J
Citation
M. Bosco et al., A new concise synthesis of nectrisine and its facile conversion to phosphonoazasugars, TETRAHEDR L, 42(45), 2001, pp. 7949-7952
Citations number
15
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
45
Year of publication
2001
Pages
7949 - 7952
Database
ISI
SICI code
0040-4039(20011105)42:45<7949:ANCSON>2.0.ZU;2-N
Abstract
The synthesis of new sugar-derived phosphonic acids from protected nectrisi ne is described. The key step is a highly stereoselective addition of a pho sphonate anion to a sugar-derived dihydropyrrole to provide a versatile syn thetic intermediate which can be functionalised in multiple ways. (C) 2001 Elsevier Science Ltd. All rights reserved.