Improved method of an unusual conversion of aliphatic amines into alcohols

Citation
Sma. Rahman et al., Improved method of an unusual conversion of aliphatic amines into alcohols, TETRAHEDR L, 42(45), 2001, pp. 8007-8010
Citations number
34
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
45
Year of publication
2001
Pages
8007 - 8010
Database
ISI
SICI code
0040-4039(20011105)42:45<8007:IMOAUC>2.0.ZU;2-X
Abstract
An improved method for the synthesis of alcohols from amines was achieved u sing a degassed diethylene glycol and KOH. Utilizing this method, facile co nversion of a cyano group, even a sterically hindered one, to a hydroxy-met hyl group was also accomplished. (C) 2001 Elsevier Science Ltd. All rights reserved.