Study on the molecular recognition properties of 4-hydroxybenzoic acid-imprinted polymer and salicylic acid-imprinted polymer

A molecularly imprinted polymer (MIP) for 4 - hydroxybenzoic acid [ P(4 - H BA)] was prepared using 4 - vinylpyridine (4 - Vpy) as a functional monomer . Its molecular recognition mechanism was studied. And a comparison was mad e to evaluate its molecular recognition ability with that of salicylic acid - imprinted polymer E P(SA) I. The result shows that the molecular recogni tion ability of P ( SA) is higher than that of P(4 - HBA). The reason is th at SA is stronger than 4 - HBA in acidity and SA can form a more stable com plex with 4 - Vpy, which makes P(SA) have a higher molecular recognition ab ility. This study confirms that it is a prerequisite that the template shou ld form a stable complex with the functional monomer in the preparation of MIP in order to obtain a MIP with high molecular recognition ability. Furth ermore, this study will be helpful for us to understand the mechanism of mo lecular imprinting and molecular recognition of MIN. Also, it will be of in structive significance for us to predict the selectivity of MIPs according to the properties of templates.